What is Hydroxytyrosol and Olive Extract

hydroxytyrosol, Olive

hydroxytyrosol, An antioxidant found in olive oil, protects blood lipids (fats) from
oxidative damage

Hydroxytyrosol is a powerful polyphenol which occurs naturally in the olive fruit, pulp, leaves and mill waste waters. Chemically, hydroxytyrosol is described as 4-(2-hydroxyethyl)-1,2-benzendiol, with an empirical formula C8H10O3. Hydroxytyrosol is a well-known minor component found in Extra Virgin Olive Oil, which is derived from hydrolysis of the polyphenol oleuropein during olive maturation and olive oil storage. The compound plays an important role (amongst other minor components) in the complex and varied flavor of olives and olive oil.1 It is also a vital component which largely adds to the stability of olive oil.2 Hydroxytyrosol is hydrophilic, and absorbed in a dose-dependent manner in humans, with absorption occurring in the small intestine and colon. Uniquely, hydroxytyrosol is the only polyphenol which is able to cross the blood brain barrier, which allows it to have a significant action to scavenge free radicals in the nervous system.

Health Benefits

Hydroxytyrosol has a potent antioxidant activity – it has one of the highest know ORAC (oxygen radical absorbance capacity) results known for a natural antioxidant. (ORAC is a method used to determine the antioxidant capacity of a food or chemical substance).

There is also evidence related to the health benefits of hydroxytyrosol in the following areas:

Anticancer activity

Hydroxytyrosol has the capacity to inhibit proliferation and promote apoptosis of several tumour cells.1 Therefore, it has been suggested that hydroxytyrosol may have anticancer effects. The exact mechanism of these effects is not well defined, and research continues in this space.

Anti-inflammatory activity

Research has shown that hydroxytyrosol can reduce the production of cytokine tumor necrosis factor alpha (TNF alpha) in animal models of inflammation.2 Animal based research has also shown that hydroxytyrosol may be able to reduce acute inflammation and associated pain.

Antimicrobial activity

In vitro experiments have shown that hydroxytyrosol has antimicrobial properties against infectious respiratory and gastrointestinal pathogens.1 It is also known that hydroxytyrosol has activity against gram positive and gram-negative bacteria. In general, phenolic compounds have been reported to have wide antimicrobial activity, such as antibacterial, antiviral and antifungal effects.2 The exact mechanism by which hydroxytyrosol exerts its antimicrobial action is not well known.

Antithrombotic activity

A human study showed that hydroxytyrosol was able to lower serum thromboxane B2 levels, leading to an anti-aggregatory platelet effect. Other research supports this finding, showing that hydroxytyrosol significantly reduces platelet aggregation.1

Antiatherogenic capacity and cardioprotective effect

It is known that hydroxytyrosol is a powerful scavenger of free radicals which allows for the reduction in oxidation of low-density-lipoproteins (LDL), potentially reducing the risk of atherosclerosis.

Retino-protective activity

Hydroxytyrosol may play a role in reducing the risk of age-related macular degeneration, however further research is required in this area to determine the exact mechanism and importance of this preliminary research finding.

Skin related effects

It is believed that oxidative stress plays a major role in UVA-induced protein damage to the skin. Preliminary research shows that hydroxytyrosol can work to prevent such UVA damage in melanoma cells.

Where I can Buy Hydroxytyrosol ?

Dihydrocaffeic Acid

Dihydrocaffeic acid

Dihydrocaffeic Acid a natural phenolic compound found in many edible and medicinal plants, Dihydrocaffeic acid is a metabolite of chlorogenic acid and has shown antioxidant, cardioprotective, and neuroprotective effects.

It is not easy to obtain by traditional chemical synthesis, We have successfully established a novel pathway and constructed an E. coli strain for the production of both Dihydrocaffeic acid and caffeic acid, bulk quantity is available now like our featured product of Caffeic Acid

 


Hangzhou Biopak  Co., Ltd is known as manufactuer of Phenolic Acids/ Polyphenols manufacturer in China, all based on innovative biosynthesis production process, and our full controlled subsidiary company in Nanchang of Jiangxi Province, is a modern plant occupying an area of 40,000 sqm.


Chemical Entity

Synonym: Dihydrocaffeic acid
3-(3,4-Dihydroxyphenyl)propionic acid
Hydrocaffeic acid
3,4-Dihydroxyhydrocinnamic acid
CAS No.: 1078-61-1
Formula: C9H10O4
Molecular Weight: 182.17 g/mol
Structure:


Application

  • Similar to many natural phenolic compounds (Caffeic Acid, Protocatechuic Acid etc.) which have attracted increasing attention for their various pharmaceutical properties and health-promoting effects. Nowadays, large-scale production of drugs or drug precursors via microbial approaches provides a promising alternative to chemical synthesis.

Caffeic Acid

Caffeic Acid

Caffeic Acid is a natural phenolic compound initially found in plants.
As a nature antioxidant and bioactive ingredients it is commonly  used for pharmaceutical, cosmetics, dermatology and aesthetic.        


Hangzhou Biopak Co Ltd is known as manufactuer of Phenolic Acids/ Polyphenols manufacturer in China, all based on innovative biosynthesis production process, and our full controlled subsidiary company in Nanchang of Jiangxi Province,   is a modern plant occupying an area of 40,000 sqm.  

 

Chemical Entity    

Synonym: 3,4-Dihydroxycinnamic acid
CAS No.: 331-39-5
Formula: C9H8O4
Molecular Weight: 180.16
Structure:
Apparance: Light yellow to yellowish brown crystal, slightly soluble in water, soluble in hot water, cold ethanol, ethyl acetate.    


Benefits:    

  • As active pharmaecutical ingredients, it prevent and cure leukopenia and thrombocytopenia, especially for those patient received chemotherapy, can result in unintended damage to organs.

  • As bioactive ingredients contribute to the inhibition of the skin photoaging process,regeneration and absorption of UVB and UVA radiation. Caffeic Acid moisturizes the skin and stimulates the synthesis of collagen and elastin fibers, rebuilding it, has a soothing and anti-imflammatory, antipigmentation effect. Caffeic acid is used for skin care product i.e. anti-wrinkle cream, sunscreen, facial mask, body scrubs, seborrheic and acne preparations.

  • Antioxidant, anti-virus, anti-cancer, and anti-inflammatory for human health and wellness.


Cosmetics Product contains Caffeic Acid:

  • Sulwhasoo Concentrated Ginseng Renewing Cream Ex

  • Sulwhasoo Concentrated Ginseng Renewing Cream

  • Dr.ForHair Folligen Shampoo Endocare Gel Light Touch

  • Heliocare 360° Mineral Tolerance Fluid SPF 50

  • Heliocare 360° Fluid Cream Spf 50+

  • Heliocare 360 Fluid Cream Spf50

  • Heliocare 360° Gel Oil-Free Spf 50

  • Heliocare 360 Color Gel Oil Free spf 50

  • Heliocare 360° Color Gel Oil-Free Spf 50

  • Heliocare 360° Mineral Fluid Spf 50

  • Heliocare 360° Airgel Spf 50+

  • Heliocare 360° Color Cushion-Beige

  • Heliocare Ultra Cream Spf 90

  • Etude House Pink Vital Water Toner

  • Etude House Pink Vital Water Cream

  • Liz K First C Serum Omg!

  • Pure Vitamin C Serum

  • Melixir Vegan Vitamin C Serum

Hydroxytyrosol

Hydroxytyrosol

Hydroxytyrosol is a powerful antioxidant that has been part of the diet of populations from the Mediterranean Basin for millennia. In recent years, the traditional Mediterranean diet has received an increasing amount of attention for its protective effects against heart disease, certain cancers, skin ailments and a good number of today’s stress and ageing related health problems. That protective function comes in large part from the antioxidant polyphenols at the basis of this kind of diet.

Hydroxytyrosol, the most active of these polyphenols, is found in olives and olive oil and is now credited for most of the beneficial effects of a Mediterranean style of eating.

It has all the support beenfits of olive oil, but it is obviously unhealthy and impractical to ingest a bouch of oil.
Hydroxytyrosol, olive leaf extract or biosynthsis source product are popular now.

Hangzhou Biopak Co Ltd is known as manufactuer of Phenolic Acids/ Polyphenols manufacturer in China, all based on innovative biosynthesis production process, and our full controlled subsidiary company in Nanchang of Jiangxi Province,, is a modern plant occupying an area of 40,000 sqm.  

Chemical Entity:

Synonym:3,4-Dihydroxyphenylethanol

3-Hydroxytyrosol
3,4-dihydroxyphenylethanol
Dihydroxyphenylethanol
2-(3,4-Di-hydroxyphenyl)-ethanol
IUPAC name: 4-(2-hydroxyethyl)-benzene-1,2-diol
CAS No.:10597-60-1
Formula: C8H10O3
Structure:
Molecular Weight:154.17
Appearance:Clear, faint yellow to light green liquid,


Benefits:

  • Excellent antioxidize effect

  • Benefits for bone growth and function, enhances the body’s absorption of minerals, and maintains bone density        

  • A certain anti-cancer effect

  • For cardiovascular drug development

  • Promotes metabolism and wound healing, improves endocrine    

Application:

  • Health care products- enhance skin elasticity, make it moist with anti-winkle and anti-aging effect

  • Prevents oxidative damage and mitochondrial dysfunction of retinal pigment epithelial cells caused by acrolein

  • Natural preservative

  • Cosmetics- reduces UV damage to the skin and delays skin aging      

  • Meal addition, energy bars, functional drinks    


Remarks: Except High Concentration 99% which is in liquid form, we also provide diluent Hydroxytyrosol as solid powder form (on carrier typical like Maltodextrin, 10%, 20%, 50%)  depending on your requirement, and easy to use

Download: 

Safe Data Sheet  – Hydroxytyrosol, 99%  

Hydroxytyrosol_Overview   

What is Hydroxytyrosol and Olive Extract