Also known as : Biotin, D-(+)-biotin, Vitamin
B7, Vitamin H, Coenzyme R, Biotina
Biotin is a water-soluble B-vitamin, a natural product found largely
in the kidney, liver, egg yolk, milk and yeast. The compound is used to
prevent symptoms of eggwhite injury in experimental
animals. Its prime medical use is in various dermatitides. Biotin is a
coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids,
isoleucine, and valine, and in gluconeogenesis. Brittle and thin fingernails
Hair loss (alopecia)
Dermatitis in the form of a scaly, red rash around the eyes, nose,
mouth, and genital area.
Neurological symptoms in adults, such as depression, lethargy, hallucination,
and numbness and tingling of the extremities
Biotin is necessary for cell growth, the production of fatty acids, and
the metabolism of fats and amino acids. Biotin assists in various metabolic
reactions involving the transfer of carbon dioxide. It may also be helpful
in maintaining a steady blood sugar level. Biotin is often recommended
as a dietary supplement for strengthening hair and nails, though scientific
data supporting this outcome are weak. Nevertheless, biotin is found in
many cosmetics and health products for the hair and skin.
Biotin deficiency typically occurs from dietary absence of the vitamin.
Consuming raw egg whites over months may result in biotin deficiency.
Deficiency can be addressed with nutritional supplementation. Deficiency
The neurological and psychological symptoms can occur with only mild deficiencies.
Dermatitis, conjunctivitis, and hair loss will generally occur only when
deficiency becomes more severe. Individuals with hereditary disorders
of biotin deficiency have evidence of impaired immune system function,
including increased susceptibility to bacterial and fungal infections.
Pregnant women tend to have a high risk of biotin deficiency. Nearly half
of pregnant women have abnormal increases of 3-hydroxyisovaleric acid,
which reflects reduced status of biotin. Several studies have reported
this possible biotin deficiency during the pregnancy may cause infants'
congenital malformations, such as cleft palate. Mice fed with dried raw
egg to induce biotin deficiency during the gestation resulted in up to
100% incidence of the infants' malnourishment. Infants and embryos are
more sensitive to the biotin deficiency. Therefore, even a mild level
of the mother's biotin deficiency that does not reach the appearance of
physiological deficiency signs may cause a serious consequence in the
Hence, D-Biotin or its preparation / premixture is used widly as food,
feed additive, it is an important vitamin supplements
D-(+)- Biotin have three chiral centers, a stereospecific synthesis
or selectively synthesis is extremely difficult and costly, The innovative
technologies used by Zhejiang Shengda Bio Pharm Co Ltd include the selection
of starting material, shorten the production process to total nine process
steps and control of costs etc.
Line Formula: C10H16N2O3S
CAS No: 58-85-5
We mainly provide below items into markets
|| Product Name
| Active Pharmaecutical Ingredient (API)
|| D-Biotin (Pure)
| Food Additive
|| 1% D-Biotin on DCP
|| REGULATION (EU) No 609/2013 OF THE EUROPEAN PARLIAMENT AND
OF THE COUNCIL of 12 June 2013 on food intended for infants and
young children, food for special medical purposes
GB 1903.25-2016 食品安全国家标准 食品营养强化剂 D-生物素
|| 2% D-Biotin on Maltodextrin
|| COMMISSION IMPLEMENTING REGULATION (EU) 2015/723 of 5 May
2015 concerning the authorisation of biotin as a feed additive for
all animal species
GB 36898-2018 饲料添加剂 D-生物素
GB/T 23180-2008 饲料添加剂 2% D-生物素
| Feed Additive
|| 10% D-Biotin on Maltodextrin
|| REGULATION (EU) No 609/2013 OF THE EUROPEAN PARLIAMENT
AND OF THE COUNCIL of 12 June 2013 on food intended for infants
and young children, food for special medical purposes
GB 1903.25-2016 食品安全国家标准 食品营养强化剂 D-生物素
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